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Digoxin, sold under the brand name Lanoxin, is a prescription drug used to help treat arrhythmia (irregular heartbeat) and improve symptoms of fatigue caused by heart failure.
Digoxin belongs to a group of drugs known as anti-arrhythmics, which work by preventing sodium from being pumped out of heart cells.
Digoxin Warnings You should not take digoxin if you: Are allergic to digoxin or any of the ingredients in the medication Have an irregular heartbeat caused by ventricular fibrillation Talk to your doctor before taking digoxin if you: Have any current or previous heart conditions, including heart attack, endocarditis (infections of the heart muscle or in the lining that surrounds the heart), heart failure, or very slow heartbeat Have low concentrations of oxygen in the body, a condition known as hypoxia Have low levels of potassium or calcium in the blood, which might reduce the effect of digoxin High levels of calcium or low levels of magnesium in the blood Have Beriberi heart disease Have thyroid disease The concentration of digoxin in your blood can vary based on many factors and could become dangerous if not kept within a certain range.
Your doctor will probably have you come in for lab work from time to time to monitor your digoxin levels.
Digoxin Use in the Elderly Digoxin is considered safe to use in the elderly as long as the dose is no greater than 0.125 milligram (mg) or 125 mcg per day.
As we age, our kidney function changes and normally slows, so our bodies can’t get rid of certain substances, like digoxin, as quickly as they once could have.
Digoxin overdose symptoms in elderly are sometimes hard to pinpoint without running laboratory tests.
Elderly people taking higher doses of digoxin may become delirious or confused and feel weak or tired.
Pregnancy and Digoxin Digoxin should only be taken by pregnant women when the risks outweigh the benefit.
Talk to your doctor if you are pregnant or might become pregnant before taking this medication.
Digoxin has been found to pass into breast milk, so talk to your doctor if you are breastfeeding or plan to breastfeed.
BasicDescription Back to Top Digoxin Side Effects Common Side Effects of Digoxin You should tell your doctor if any of the following side effects become severe or don’t go away: Dizziness Changes in mood and mental alertness, including confusion, depression and lost interest in usual activities Anxiety Nausea, vomiting and diarrhea Headache Rash Growth or enlargement of breast tissue in men (gynecomastia) Weakness Serious Side Effects of Digoxin You should call your doctor immediately if you experience any of the following serious side effects: Changes in heart rhythm, including irregular heartbeat Fast or racing heartbeat Heart stopping or flat-lining (asystole) Problems with electrical functioning of the heart known as heart block Visual problems, including blurry vision and yellow halos Low platelet count Back to Top Digoxin Interactions Digoxin interacts with many drugs.
As always, share with your doctor and pharmacist all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you’re taking.
You should not take Digoxin if you are taking any herbal supplements belonging to the squill family, such as white quill or Mediterranean squill.
Before taking digoxin, tell your doctor if you are taking any of the following medications: Drugs for irregular heartbeat like: Pacerone, Nexterone, or Cordarone ( amiodarone ), Betapace or Betapace AF ( sotalol ), Tikosyn (dofetilde), Multaq (dronedarone), procainamide, or flecainide Aspirin (both tablet and suppository forms) Beta blockers like Zebeta or Ziac ( betaxolol ),Toprol XL or Lopressor ( metoprolol ), Tenormin ( atenolol ), and Bystolic ( nebivolol ) Heartburn medications like Prilosec ( omeprazole ), Nexium ( esomeprazole ), Aciphex ( rabeprazole ), Protonix ( pantoprazole ), and Dexilant (deslansoprazole) Other heartburn medications like Pepcid ( famotidine ) and Tums ( calcium carbonate ) The herbal supplement Lily of the Valley Macrolide antibiotics like Ery-Tab ( erythromycin ) and Biaxin ( clarithromycin ) Neoral, Sandimmune, and Gengraf ( cyclosporine ) Digoxin and Alcohol Digoxin can cause sleepiness, confusion, and problems with balance; drinking while taking digoxin could worsen these side effects.
For best results, avoid drinking alcohol while taking digoxin.
Digoxin and Grapefruit Juice Grapefruit juice can lessen digoxin’s ability to work.
You should avoid eating grapefruit or drinking grapefruit juice while taking digoxin.
Back to Top Digoxin Dosage Digoxin comes in tablets and liquids for injection into muscles and veins.
Only trained medical professionals can give digoxin injections to a patient.
Tablets are available in doses of 0.125 milligram (mg) and 0.250 mg.
Sometimes, the doses may be written in micrograms (mcg): 120 mcg and 250 mcg.
Your doctor will draw blood to determine how much digoxin you should be taking each day.
This will also determine the maximum amount of digoxin you are to receive.
You should be consistent in taking digoxin the same time every day.
Digoxin Overdose If you suspect an overdose, contact a poison control center or emergency room immediately.
You can get in touch with a poison control center at (800) 222-1222.
In certain situations of severe overdose, medical professionals may give you an antidote to digoxin.
Missed Dose of Digoxin If you miss a dose of digoxin, try to take it as soon as you remember.
If it’s less than 12 hours before your next scheduled dose, skip the missed dose and resume your regular dosing schedule.
Don’t take two doses of the medication at the same time.
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