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Buspirone is a prescription medication used to treat anxiety.
It belongs to a group of anti-anxiety drugs called anxiolytics, but it seems to work somewhat differently than other drugs in the class.
Though researchers don’t know exactly how buspirone reduces anxiety, they believe it competes with serotonin and dopamine, which are neurotransmitters (chemical brain messengers) involved with causing anxiety symptoms.
Buspirone isn’t for treating occasional stress associated with everyday life.
Rather, doctors prescribe buspirone for anxiety disorder and short-term relief of anxiety symptoms.
You may be diagnosed with anxiety disorder if you have at least one full month of anxiety symptoms such as shakiness, tension, irritability, dizziness, worry, fear, upset stomach, and trouble sleeping.
The Food and Drug Administration (FDA) approved buspirone in 1986 for the drug manufacturer Bristol-Myers Squibb, under the brand name BuSpar.
In 2001, the FDA approved a generic version of buspirone for several drug manufacturers, and Bristol-Myers Squibb discontinued the brand name BuSpar.
Recently, researchers began studying other possible uses for buspirone.
A 2013 study published in the journal International Review of Neurobiology found that buspirone may be an effective treatment for Tourette syndrome, a brain disorder that causes people to make uncontrolled and repetitive movements and sounds (tics).
An earlier study, published in 2011 in the journal Therapeutic Advances in Neurological Disorders, also found that buspirone may reduce the frequency and severity of Tourette syndrome tics.
Buspirone Warnings You should not take buspirone if you are taking a monoamine oxidase inhibitor (MAOI), a type of drug used for treating depression.
Examples of MAOIs include phenelzine (Nardil) and tranylcypromine (Parnate).
Taking buspirone with MAOIs can cause a dangerous increase in blood pressure.
Research has shown that the safety of buspirone does not vary by age.
For short-term use (no more than six weeks), it’s as safe in people 65 and older as in other adults and in children six to 17.
However, long-term safety of buspirone in children is unknown.
Let your doctor know if you’re taking other medications for anxiety.
Many anxiety medications can be dangerous if you stop taking them suddenly.
They can cause a dangerous withdrawal reaction that could include anxiety, insomnia, abdominal pain, and seizure.
Switching from one of these drugs to buspirone will not prevent a withdrawal reaction because buspirone does not act like these other medications.
Instead, you have to taper down the dose of the drugs gradually.
Your doctor should know if you have certain conditions so he or she can decide if buspirone is the right drug for you.
They include: Kidney disease Liver disease Drug or alcohol abuse Pheochromocytoma (a rare tumor that causes high blood pressure ) Buspirone ‘High’ and Addiction Numerous online and anecdotal reports have suggested that some people abuse buspirone for a narcotic-like “high.” Buspirone abuse can result in: Hallucinations Nausea or vomiting Euphoria Memory loss Lack of coordination Fatigue Take buspirone only as directed by your doctor, and keep this and all other drugs away from children, teenagers, and anyone for whom the drug has not been prescribed.
Buspirone and Pregnancy Buspirone has not been tested enough to know whether it’s safe to take during pregnancy.
Women should let their doctor know if they are or may become pregnant before taking buspirone.
Also, the drug may pass through breast milk, but it’s not known whether it’s safe to take buspirone while breastfeeding.
BasicDescription Back to Top Buspirone Side Effects Let your doctor know if you have any side effects.
The most common side effects of buspirone are: Nausea Headache Dizziness Nervousness Lightheadedness Excitement Less common side effects include: Constipation Diarrhea Upset stomach Dry mouth Depression Fatigue Trouble sleeping Weakness Numbness Serious side effects can occur.
If you have any of these side effects, call your doctor right away: Rash or hives Itching Heart palpitations or rapid heartbeat Blurred vision Abnormal and uncontrolled body movements Anger, hostility, or confusion Muscle stiffness Inability to pass urine Back to Top Buspirone Interactions Some drugs may affect the way buspirone works, and buspirone may affect other drugs you are taking.
It’s very important to let your doctor know about all drugs you are taking, including over-the-counter drugs, vitamins, and supplements.
Medications that are known to interact with buspirone include: MAOIs Selective serotonin reuptake inhibitors (SSRIs) such as nefazodone (Serzone) and trazodone (Oleptro) The blood thinner warfarin ( Coumadin ) Drugs used to treat seizures, such as phenytoin ( Dilantin ) and carbamazepine ( Tegretol ) Benzodiazepines that are used to treat anxiety and insomnia, such as diazepam (Valium) and triazolam (Halcion) Muscle relaxants like cyclobenzaprine (Flexeril) Drugs used to treat fungal infections, including itraconazole (Sporanox, Onmel), itraconazole (Sporanox), and ketoconazole (Nizoral) Certain antibiotics, including erythromycin (E.E.S., E-Mycin, Erythrocin) and rifampin (Rifadin, Rimactane) Steroids such as prednisone The heartburn drug cimetidine (Tagamet) The HIV drug ritonavir (Norvir) Drugs used to treat high blood pressure and chest pain, including diltiazem (Cardizem) and verapamil (Calan, Verelan, Covera-HS) The antipsychotic drug haloperidol ( Haldol ) Other Buspirone Interactions Buspirone may cause drowsiness and confusion.
Because of that, you shouldn’t drive, operate dangerous machinery, or participate in any risky activities until you know how buspirone affects you.
You should also avoid drinking alcohol while taking buspirone.
Don’t drink large amounts of grapefruit juice with buspirone.
Back to Top Buspirone Dosage Buspirone comes in tablets of 5, 10, 15, or 30 milligrams (mg).
The tablets have a scored mark down the middle so you can split a pill in half if necessary.
A typical dose starts at 7.5 mg every 12 hours.
Your doctor may increase your daily dose by 5 mg every few days if needed.
An average daily dose is 20 to 30 mg a day in divided doses.
The maximum daily dose is 60 mg.
Always take buspirone at the same time each day, with or without food.
Buspirone Overdose An overdose of buspirone may cause: Drowsiness Nausea Vomiting Dizziness Blurred vision If an overdose occurs, call a poison control center at 1-800-222-1222.
If you or someone else has any severe symptoms after an overdose, call 911.
Missed Dose of Buspirone Take buspirone exactly as directed by your doctor.
Don’t stop taking buspirone on your own.
It may take a few weeks to feel the full effect.
If you miss a dose of buspirone, take the missed dose as soon as you remember.
If it’s almost time for your next regular dose, however, skip the missed dose.
Don’t double your dose to make up for the missed one.
Back to Top Buspirone Pictures Buspirone 15 mg-TEV, white, rectangular, Buspirone 5 mg-WAT, white, oval, BuSpar 5 mg, white, rectangular, Buspirone 30 mg-TEV, white, rectangular, Buspirone 10 mg-MYL, white, oval, Buspirone 10 mg-ETH, yellow, oval, Buspirone 5 mg-MYL, white, oval, Buspirone 15 mg-MYL, white, oblong, Buspirone 15 mg-WAT, white, oval, Buspirone 5 mg-PAR, peach, oval, Buspirone 5 mg-ETH, yellow, oval, Buspirone 15 mg-ETH, yellow, oblong, BuSpar 15 mg, white, rectangular, Buspirone 5 mg-TEV, white, round, Buspirone 10 mg-TEV, white, round, Buspirone 10 mg-IVA, white, oval, BuSpar 10 mg, white, rectangular, Buspirone 5 mg-IVA, white, oval, Buspirone 15 mg-IVA, white, oblong, Buspirone 30 mg-MYL, white, oblong, Buspirone 10 mg-WAT, white, oval, Buspirone 15 mg-PAR, peach, rectangular,
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