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Nortriptyline is a medication used to treat depression.
The brand names for this antidepressant are Aventyl and Pamelor.
The drug is in an older class of antidepressants known as tricyclic antidepressants.
Nortriptyline is sometimes also used to treat panic disorders and a condition known as post-herpetic neuralgia (burning pains that persist after a shingles infection).
It may also be used to help people quit smoking and to treat attention deficit hyperactivity disorder (ADHD).
This medicine works by increasing amounts of neurotransmitters (natural substances in the brain).
It comes in an oral capsule and liquid form.
Nortriptyline was approved by the Food and Drug Administration (FDA) in 1964.
Nortriptyline Black-Box Warning Nortriptyline, like other antidepressants, is required by the FDA to carry a black-box warning because of an increased risk of suicide.
In clinical studies, a small number of children, teenagers, and young adults who took antidepressants such as nortriptyline became suicidal.
However, experts are unsure about the implications of this risk.
Children who are younger than 18 should not typically take nortriptyline, but a doctor may decide that this medication is the best choice for a child’s condition.
Your mental health may change in unexpected ways while taking nortriptyline and you may become suicidal, even if you are an adult.
You or a family member should call your doctor right away if you experience any of the following symptoms: Thoughts of harming or killing yourself New or worsening depression Extreme worry Agitation Panic attacks Difficulty falling asleep or staying asleep Irritability Acting without thinking Severe restlessness Abnormal excitement Aggressive behavior Your doctor will likely start you on a low dose of nortriptyline and gradually increase your dose.
You should continue to take this medication even if you feel well.
If you suddenly stop taking nortriptyline, you may experience withdrawal symptoms such as nausea, headache, and weakness.
Other Nortriptyline Warnings You should tell your doctor if you have or have ever had any of the following conditions before taking nortriptyline: Heart attack Glaucoma Enlarged prostate Difficulty urinating Diabetes Seizures Schizophrenia Overactive thyroid gland Liver, kidney, or heart disease Also tell your doctor if you are taking a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), linezolid ( Zyvox ), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate).
You should also alert your physician if you have stopped taking an MAOI within the past 14 days.
If you stop taking nortriptyline, you should wait 14 days or longer before you start taking an MAOI.
Nortriptyline ‘High’ and Abuse There have been some anecdotal and online reports that taking large doses of nortriptyline can lead to a “high” or hallucinations in some people.
Trying to get a high from nortriptyline or any prescription medication is dangerous and could lead to severe side effects or a life-threatening overdose.
Take nortriptyline only as directed, and keep this and all other drugs away from children, teenagers, and anyone for whom the drug has not been prescribed.
Pregnancy and Nortriptyline There is not enough data available to show that nortriptyline is safe to take while pregnant or breastfeeding.
However, a doctor may prescribe this medication to a pregnant woman if the benefits outweigh the risks.
If you are pregnant, might become pregnant, or are breastfeeding, talk with your doctor about the benefits and risks of using nortriptyline.
BasicDescription Back to Top Nortriptyline Side Effects Common Side Effects of Nortriptyline You should tell your doctor if any of the following side effects are severe or do not go away: Drowsiness Weakness or fatigue Nausea Nightmares Excitement or anxiety Changes in weight or appetite Dry mouth Constipation Frequent urination or difficulty urinating Blurred vision Excessive sweating Change in sex drive or ability Serious Side Effects If you experience any of the following serious side effects, call your doctor immediately or seek emergency medical care: Slow or difficult speech Shuffling walk Uncontrollable shaking of a part of the body Difficulty breathing or swallowing Rash Irregular heartbeat Fever Yellowing of the skin or eyes ( jaundice ) Jaw, neck, and back muscle spasms Back to Top Nortriptyline Interactions You should tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you are taking, especially: Blood thinners such as warfarin ( Coumadin, Jantoven) Antihistamines Chlorpropamide (Diabinese) Cimetidine (Tagamet) Flecainide (Tambocor) Guanethidine (Ismelin) Lithium (Eskalith, Lithobid) Drugs for high blood pressure, seizures, Parkinson’s disease, diabetes, asthma, nausea, mental illness, colds, or allergies Methylphenidate ( Ritalin ) Muscle relaxants Propafenone (Rythmol) Quinidine Sedatives Selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram ( Lexapro ), fluoxetine ( Prozac, Sarafem), fluvoxamine ( Luvox ), paroxetine (Paxil), and sertraline ( Zoloft ) Sleeping pills Thyroid medication Tranquilizers Additionally, avoid unnecessary or prolonged exposure to the sun while taking nortriptyline, as it may make your skin more sensitive to sunlight.
Nortriptyline and Alcohol Talk to your doctor about consuming alcohol while taking this medication.
Nortriptyline may make you drowsy.
You should not drive a car or operate machinery until you know how this drug will affect you.
Back to Top Nortriptyline Dosage Adults: The typical dose is 25 milligrams (mg), given three to four times a day.
Adolescents: The typical dose is 30 to 50 mg, once daily or divided into doses.
Nortriptyline Overdose If you suspect an overdose, contact a poison control center or emergency room immediately.
You can get in touch with a poison control center at (800) 222-1222.
Missed Dose of Nortriptyline If you miss a dose of nortriptyline, take it as soon as you remember.
However, if it is almost time for your next dose, skip the missed dose and continue on your regular schedule.
Do not “double up” to make up for a missed one.
Back to Top Nortriptyline Pictures Nortriptyline 25 mg-TEV, orange/white, capsule, Nortriptyline 10 mg-WAT, green/white,, Nortriptyline 75 mg-WAT, green, capsule, Nortriptyline 75 mg-GG, green, capsule, Pamelor 10 mg, orange/yellow, capsule, Nortriptyline 50 mg-TEV, white, capsule, Nortriptyline 50 mg-GG, white,, Nortriptyline 10 mg-MYL, red, capsule, Nortriptyline 10 mg-WAT, green/white, capsule, Nortriptyline 25 mg-GG, white,, Nortriptyline 10 mg-TEV, orange/white, capsule, Nortriptyline 75 mg-TEV, orange, capsule, Nortriptyline 50 mg-MYL, orange/yellow, capsule, Nortriptyline 75 mg-TEV, orange,, Nortriptyline 50 mg-WAT, white, capsule, Nortriptyline 25 mg-MYL, orange, capsule, Nortriptyline 75 mg-MYL, brown/orange, capsule, Pamelor 25 mg, orange/white,, Nortriptyline 25 mg-WAT, green/white, capsule,
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