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Additional information about the drug Pioglitazone

Pioglitazone, Metformin Hydrochloride Oral Tablet Drug. Pioglitazone, Metformin Hydrochloride Oral tablet drug summary.

  • Suitable glucose production inhibitors include, but are not limited to, acarbose, acetohexamide, chlorpropamide, glipizide, glyburide, metformin, miglitol, nateglinide, pioglitazone, rosiglitazone, tolbutamide, tolazamide, and mixtures thereof.
  • Concomitant administration of clarithromycin and colchicine is contraindicated in patients with renal or hepatic impairment (see CONTRAINDICATIONS and PRECAUTIONS, Drug Interactions ). With certain hypoglycemic drugs such as nateglinide, pioglitazone, repaglinide and rosiglitazone, inhibition of CYP3A enzyme by clarithromycin may be involved and could cause hypoglycemia when used concomitantly.INR and prothrombin times should be frequently monitored while patients are receiving clarithromycin and oral anticoagulants concurrently. Cases of rhabdomyolysis have been reported in patients taking clarithromycin concomitantly with these statins.
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