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This inhibition decreases the expression of proinflammatory cytokines, such as IL-2. Cyclosporine A is a commercially available under the trade name NEORAL from Novartis.Methods of providing cyclosporine formulations with improved bioavailability are described in U.S. Patent Nos. 4,388,307, 6,468,968, 5,051,402, 5,342,625, 5,977,066, and 6,022,852.

  • Additional analysis of the importance of these morphologic subtypes was undertaken in the NIH FSGS Clinical Trials cohort of 138 patients with steroid-resistant primary FSGS. 17 The trial participants were randomly assigned to receive mycophenolate mofetil and dexamethasone versus cyclosporine, in addition to standard angiotensin-converting-enzyme (ACE) inhibitor or angiotensin-receptor blocker (ARB) therapy.
  • A case of membranous nephropathy with primary biliary cirrhosis and cyclosporine-induced remission, Intern Med, 2011, vol. 50 (pg. 233 – 238 ) Google Scholar Crossref Search ADS PubMed 3 Vlassopoulos D, Divari E, Savva S, et al.
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